Finding advances efforts to tailor drugs to individual patientsGenes at the heart of bad outcomes in high blood pressure patientsThe discovery, reported at the annual Scientific Sessions of the American Heart Association, brings scientists a step closer toward determining how certain genes influence the development of hypertension and the bad outcomes associated with the condition. Just as discriminating shoppers buy made-to-order suits to flatter their figure, this type of research may someday enable patients to seek out medicine tailored to fit, based not on their size and shape but on their genetic makeup...
Identifying genetic risk factors is only the first step, said epidemiologist Sharon Kardia, Ph.D., director of the Public Health Genetics Program at the University of Michigan School of Public Health.
"Large research studies need to be undertaken to prove that genetic risk can be reduced through medical or public health interventions. Second, this whole new realm of genomic medicine greatly expands the responsibilities of doctors, nurses and pharmacist to assure the proper use of genetic information in prescribing, dispensing and administering drug therapies," Kardia said. "Lastly, we have to tread lightly until we have assurances that people's genetic information will be properly protected so that identifying someone as more expensive or difficult to treat won't result in insurance or perhaps job discrimination. As Dr. Johnson's research illustrates, we now have good evidence that we should be investing in genetics education, regulation and social engagement so that we can move these results to the next level - namely, decreasing health-care costs and saving lives."